CYP-001 GvHD Trial Primary Evaluation Results

Open PDF
Stock Cynata Therapeutics Ltd (CYP.ASX)
Release Time 17 Jun 2026, 12:05 p.m.
Price Sensitive Yes
 Cynata Therapeutics CYP-001 GvHD Trial Results
Key Points
  • No safety concerns identified
  • No significant differences in primary or key secondary endpoints
  • Trial terminated early due to disappointing results
Full Summary

Cynata Therapeutics Limited (ASX: CYP) announced the primary evaluation results of its Phase 2 clinical trial of CYP-001 in patients with high-risk acute graft versus host disease (HR-aGvHD). The trial, which enrolled 65 patients across Australia, the USA, and Europe, found no safety concerns and no significant differences between the active and control groups in primary or key secondary endpoints. The trial was terminated early due to these disappointing results. Cynata will remain under voluntary suspension from the ASX pending the results of the Phase 3 SCUlpTOR trial of CYP-004 in patients with osteoarthritis of the knee.